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Index > Protein center > TJP1(Gene name) > Dog
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  • TJP1 (Gene name),
  • Tight junction protein ZO-1 (Protein name ),  ZO1_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TJP1(ZO1);
    Protein name:
    Tight junction protein ZO-1;
    Alternative:
    Zona occludens protein 1;Tight junction protein 1;Zonula occludens protein 1;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Homodimer, and heterodimer with TJP2/ZO-2 and TJP3/ZO-3. with OCLN, CALM, claudins, CGN/cingulin, CXADR, GJA12, GJD3 and UBN1. Interacts (via ZU5 domain) with CDC42BPB and GCOM1. Interacts (via PDZ domain) with GJA1 (By similarity). Interacts with HSPA4.
    Function:
    The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Cytoplasmic side Cell junction tight junction Cell junction Cell junction gap junction Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.
    Protein Attributes:
    Sequence length:
    1769
    Sequence:
    50:
    MSARAAAAKN | TAMEETAIWE | QHTVTLHRAP | GFGFGIAISG | GRDNPHFQSG | 
    100:
    ETSIVISDVL | KGGPAEGQLQ | ENDRVAMVNG | VSMDNVEHAF | AVQQLRKSGK | 
    150:
    NAKITIRRKK | KVQIPVSRPD | PEPVSENEDS | YDEEVHDPRS | SRGGLVSRRS | 
    200:
    EKSWARDRSA | SRERSLSPRS | DRRSVASSQP | PKPTKVTLVK | SRKNEEYGLR | 
    250:
    LASHIFVKEI | SQDSLAARDG | NIQEGDVVLK | INGTVTENMS | LTDAKTLIER | 
    300:
    SKGKLKMVVQ | RDERATLLNV | PDLSDSIHSA | NASERDDISE | IQSLASDHSG | 
    350:
    RSHDRPPRHS | RSRSPDQRSE | PSDHSRHSPQ | QPSSGSLRSR | EEERISKPGA | 
    400:
    VSTPVKHADD | HTHKTVEEVV | VERNEKQAPS | LPEPKPVYAQ | VGQPDVDLPV | 
    450:
    SPSDGVLPNS | THEDGILRPS | MKLVKFRKGD | SVGLRLAGGN | DVGIFVAGVL | 
    500:
    EDSPAAKEGL | EEGDQILRVN | NVDFTNIIRE | EAVLFLLDLP | KGEEVTILAQ | 
    550:
    KKKDVYRRIV | ESDVGDSFYI | RTHFEYEKES | PYGLSFNKGE | VFRVVDTLYN | 
    600:
    GKLGSWLAIR | IGKNHKEVER | GIIPNKNRAE | QLASVQYTLP | KTAGGDRADF | 
    650:
    WRFRGLRSSK | RNLRKSREDL | SAQPVQTKFP | AYERVVLREA | GFLRPVTIFG | 
    700:
    PIADVAREKL | AREEPDIYQI | AKSEPRDAGT | DQRSSGIIRL | HTIKQIIDQD | 
    750:
    KHALLDVTPN | AVDRLNYAQW | YPIVVFLNPD | SKQGVKTMRM | RLCPESRKSA | 
    800:
    RKLYERSHKL | RKNNHHLFTT | TINLNSMNDG | WYGALKEAIQ | QQQNQLVWVS | 
    850:
    EGKADGATSD | DLDLHDDRLS | YLSAPGSEYS | MYSTDSRHTS | DYEDTDTEGG | 
    900:
    AYTDQELDET | LNDEVGTPPE | SAITRSSEPV | REDSSGMHHE | NQTYPPYSPQ | 
    950:
    AQPQPIHRID | SPGFKTASQQ | KAEASSPVPY | LSPETNPASS | TSAVNHNVTL | 
    1000:
    TNVRLEGPTP | APSTSYSPQA | DSLRTPSTEA | AHIMLRDQEP | SLPSHVEPAK | 
    1050:
    VYRKDPYPEE | MMRQNHVLKQ | PAVGHPGQRP | DKEPNLSYES | QPPYVEKQAN | 
    1100:
    RDLEQPTYRY | DSSSYTDQFS | RNYDHRLRYE | ERIPTYEEQW | SYYDDKQPYQ | 
    1150:
    PRPSLDNQHP | RDLDSRQHPE | ESSERGSYPR | FEEPAPLSYD | SRPRYDQPPR | 
    1200:
    TSTLRHEEQP | TPGYDMHNRY | RPEAQSYSSA | GPKASEPKQY | FDQYPRSYEQ | 
    1250:
    VPSQGFSSKA | GHYEPLHGAA | VVPPLIPASQ | HKPEVLPSNT | KPLPPPPTLT | 
    1300:
    EEEEDPAMKP | QSVLTRVKMF | ENKRSASLEN | KKDENHTAGF | KPPEVASKPP | 
    1350:
    GAPIIGPKPT | PQNQFSEHDK | TLYRIPEPQK | PQMKPPEDIV | RSNHYDPEED | 
    1400:
    EEYYRKQLSY | FDRRSFENKP | STHIPAGHLS | EPAKPVHSQN | QTNFSSYSSK | 
    1450:
    GKSPEADAPD | RSFGEKRYEP | VQATPPPPPL | PSQYAQPSQP | GTSSSLALHT | 
    1500:
    HAKGAHGEGN | SISLDFQNSL | VSKPDPPPSQ | NKPATFRPPN | REDTVQSTFY | 
    1550:
    PQKSFPDKAP | VNGAEQTQKT | VTPAYNRFTP | KPYTSSARPF | ERKFESPKFN | 
    1600:
    HNLLPSETAH | KPDLSSKAPA | SPKTLAKAHS | RAQPPEFDSG | VETFSIHADK | 
    1650:
    PKYQMNNLST | VPKAIPVSPS | AVEEDEDEDG | HTVVATARGV | FNNNGGVLSS | 
    1700:
    IETGVSIIIP | QGAIPEGVEQ | EIYFKVCRDN | SILPPLDKEK | GETLLSPLVM | 
    1750:
    CGPHGLKFLK | PVELRLPHCA | SMTPDGWSFA | LKSSDSSSGD | PKTWQNKCLP | 
    1769:
    GDPNYLVGAN | CVSVLIDHF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Tight junction protein ZO-1
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    E9600h
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    96T
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    ELISA Kit for Dog Tight junction protein ZO-1
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    E9600d
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    96T
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    ELISA Kit for Dog Tight junction protein ZO-1
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    E9600m
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    MSDS:
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    96T
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    CLIA Kit for Dog Tight junction protein ZO-1
    Cat.:
    U9600h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Tight junction protein ZO-1
    Cat.:
    U9600m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Dog Tight junction protein ZO-1
    Cat.:
    U9600d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Dog Tight junction protein ZO-1
    Cat.:
    P9600Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Tight junction protein ZO-1
    Polyclonal Antibody for Dog Tight junction protein ZO-1
    Cat.:
    P9600Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog Tight junction protein ZO-1
    Monoclonal Antibody for Dog Tight junction protein ZO-1
    Monoclonal Antibody for Dog Tight junction protein ZO-1
    Protein for Dog Tight junction protein ZO-1
    Protein for Dog Tight junction protein ZO-1
    Protein for Dog Tight junction protein ZO-1

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Cocker spaniel.
      tissue: Kidney.
    2. 2.
      "The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB."
      Tsapara A. , Matter K. , Balda M.S.
      Mol. Biol. Cell17:1322-1330(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HSPA4
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